mir-166 microRNA precursor

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mir-166 microRNA precursor
RF00075.jpg
Identifiers
Symbol mir-166
Rfam RF00075
miRBase MI0000201
miRBase family MIPF0000004
Other data
RNA type Gene; miRNA
Domain(s) Eukaryota
GO 0035195 0035068
SO 0001244
PDB structures PDBe

The plant mir-166 microRNA precursor is a small non-coding RNA gene. This microRNA (miRNA) has now been predicted or experimentally confirmed in a wide range of plant species.[1] microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product.[2] In this case the mature sequence comes from the 3' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences.[3] The mature products are thought to have regulatory roles through complementarity to messenger RNA.

References[edit]

  1. ^ "miRNA gene family: MIR166". mirBASE. University of Manchester. Retrieved 5 September 2011. 
  2. ^ Ambros, V (2001). "microRNAs: tiny regulators with great potential". Cell. 107 (7): 823–826. doi:10.1016/S0092-8674(01)00616-X. PMID 11779458. 
  3. ^ Reinhart, BJ; Weinstein EG; Rhoades MW; Bartel B; Bartel DP (2002). "MicroRNAs in plants". Genes Dev. 16 (13): 1616–1626. doi:10.1101/gad.1004402. PMC 186362Freely accessible. PMID 12101121. 

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