mir-194 microRNA precursor family

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mir-194 microRNA precursor family
Symbol mir-194
Rfam RF00257
miRBase MI0000488
miRBase family MIPF0000055
Other data
RNA type Gene; miRNA
Domain(s) Eukaryota
GO 0035195 0035068
SO 0001244

In molecular biology, miR-194 microRNA precursor is a small non-coding RNA gene that regulated gene expression. Its expression has been verified in mouse (MI0000236, MI0000733)[1] and in human (MI0000488, MI0000732).[2] mir-194 appears to be a vertebrate-specific miRNA and has now been predicted or experimentally confirmed in a range of vertebrate species (MIPF0000055). The mature microRNA is processed from the longer hairpin precursor by the Dicer enzyme. In this case, the mature sequence is excised from the 5' arm of the hairpin.

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  1. ^ Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T (Feb 2003). "New microRNAs from mouse and human". Rna. 9 (2): 175–9. PMC 1370382Freely accessible. PMID 12554859. doi:10.1261/rna.2146903. 
  2. ^ Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ (Oct 2003). "Reduced accumulation of specific microRNAs in colorectal neoplasia". Molecular Cancer Research. 1 (12): 882–91. PMID 14573789. 

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