The bridge is over Ceyhan River (Pyramus of antiquity) between the Yakapınar (Mopsuestia of antiquity) and Geçitli at . Presently it is on the road which connects the main highway to Mediterranean Sea coast. The distance to Adana is 25 kilometres (16 mi).
In the Middle Ages, Mopsuestia was a big city and the bridge was built on one of the most active trade roads to east. It was commissioned by the Roman emperor Flavius Julius Constantius (better known as Constantius II) in the fourth century. It was restored by the Byzantine emperor Justinian I in the sixth century. It was again renovated in 743 and 840. The bridge suffered damage in the 1998 Adana–Ceyhan earthquake. But it was restored.
The building material is face stone. There are 9 arches. After the last restoration following the earthquake it is still in use.