Molybdenum cofactor

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Molybdenum cofactor has two meanings, which are sometimes used interchangeably:[1]

  • Molybdopterin, the organophosphate-dithiolate ligand that binds Mo and W in most molybdenum-containing and tungsten-containing proteins. It contains no molybdenum.
  • FeMoco, the metal cluster in nitrogenases that contains Fe, Mo, and S.


  1. ^ Schwarz, Guenter; Mendel, Ralf R.; Ribbe, Markus W. (2009). "Molybdenum cofactors, enzymes and pathways". From Nature. 460: 839–847. doi:10.1038/nature08302.CS1 maint: Uses authors parameter (link)