Wright was born to Garry and Lynette Wright in San Antonio, Texas. She has an older brother named Gerard. Her family later moved to Woodbridge, Virginia. She attended Forest Park High School. At Forest Park, she averaged 22.6 points, 9.0 rebounds, 6.8 assists and 4.0 steals per game. She was also the Gatorade Virginia Player of the Year and was ranked No. 2 guard and No. 11 player overall in the nation.
Wright was named a WBCA All-American. She participated in the 2006 WBCA High School All-America Game, where she scored eleven points, and earned MVP honors for the White team.
Wright attended the University of Virginia. In her freshman year as a Cavalier she was named the ACC Rookie of the Year. In the 2007-08 season she was named to the ACC All-Defensive Team and also notched her 1000th point. She missed being named to the All-ACC first team by two points that season. As a junior, Wright was named to the All-ACC defensive team and was also rewarded with a spot on the All-ACC first team as the league's top scorer. As a senior Wright was named ACC Player of the Year, ACC Defensive Player of the Year, and National Defensive Player of the Year.
Wright was selected as a member of the USA Women's U19 team which won the gold medal at the FIBA U19 World Championship in Bratislava, Slovakia. The event was held in July and August 2007, when the USA team defeated Sweden to win the championship. Wright averaged 9.8 points per game and led the team in steals with 21.
In 2011 and 2012, Wright played off the bench, backing up at both guard and forward. She expanded her role in 2013, becoming the primary backup at shooting guard and point guard, averaging 9.0 points per game.
Wright has twice won WNBA titles, in 2011 and 2013.