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Classification and external resources
ICD-9-CM 288.59
DiseasesDB 29083

Monocytopenia is a form of leukopenia associated with a deficiency of monocytes. The causes of monocytopenia include: acute infections, stress, treatment with glucocorticoids, aplastic anemia, hairy cell leukemia, acute myeloid leukemia, treatment with myelotoxic drugs and genetic syndromes, as for example MonoMAC syndrome.[1]

It has been proposed as a measure to predict neutropenia,[2] though some research indicates that it is less effective than lymphopenia.[3]


  1. ^ Harrison's principles of internal medicine. New York: McGraw-Hill. 2005. p. 356. ISBN 0-07-140235-7. 
  2. ^ Kondo M, Oshita F, Kato Y, Yamada K, Nomura I, Noda K (1999). "Early monocytopenia after chemotherapy as a risk factor for neutropenia". Am. J. Clin. Oncol. 22 (1): 103–5. doi:10.1097/00000421-199902000-00025. PMID 10025393. 
  3. ^ Oguz A, Karadeniz C, Ckitak EC, Cil V (2006). "Which one is a risk factor for chemotherapy-induced febrile neutropenia in childhood solid tumors: early lymphopenia or monocytopenia?". Pediatr Hematol Oncol. 23 (2): 143–51. doi:10.1080/08880010500457673. PMID 16651243.