Methylamine-corrinoid protein Co-methyltransferase
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|Methylamine-corrinoid protein Co-methyltransferase|
|PDB structures||RCSB PDB PDBe PDBsum|
Methylamine-corrinoid protein Co-methyltransferase (EC 184.108.40.206, mtmB (gene), monomethylamine methyltransferase) is an enzyme with systematic name monomethylamine:5-hydroxybenzimidazolylcobamide Co-methyltransferase. This enzyme catalyses the following chemical reaction
- methylamine + [Co(I) methylamine-specific corrinoid protein] [methyl-Co(III) methylamine-specific corrinoid protein] + ammonia
This enzyme is involved in methanogenesis from methylamine.
- Burke, S.A.; Krzycki, J.A. (1997). "Reconstitution of Monomethylamine:Coenzyme M methyl transfer with a corrinoid protein and two methyltransferases purified from Methanosarcina barkeri". J. Biol. Chem. 272: 16570–16577. doi:10.1074/jbc.272.26.16570. PMID 9195968.
- Burke, S.A.; Lo, S.L.; Krzycki, J.A. (1998). "Clustered genes encoding the methyltransferases of methanogenesis from monomethylamine". J. Bacteriol. 180: 3432–3440. PMC . PMID 9642198.
- Krzycki, J.A. (2004). "Function of genetically encoded pyrrolysine in corrinoid-dependent methylamine methyltransferases". Curr. Opin. Chem. Biol. 8: 484–491. doi:10.1016/j.cbpa.2004.08.012. PMID 15450490.
- Methylamine---corrinoid protein Co-methyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)