Mucinaminylserine mucinaminidase

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mucinaminylserine mucinaminidase
Identifiers
EC number 3.2.1.110
CAS number 59793-96-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a mucinaminylserine mucinaminidase (EC 3.2.1.110) is an enzyme that catalyzes the chemical reaction

D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine

Thus, the two substrates of this enzyme are D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine and H2O, whereas its two products are D-galactosyl-3-N-acetyl-beta-D-galactosamine and L-serine.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine mucinaminohydrolase. Other names in common use include endo-alpha-N-acetylgalactosaminidase, and endo-alpha-N-acetyl-D-galactosaminidase.

References[edit]

  • Bhavanandan VP, Umemoto J, Davidson EA (1976). "Characterization of an endo-alpha-N-acetyl galactosaminidase from Diplococcus pneumoniae". Biochem. Biophys. Res. Commun. 70 (3): 738–45. PMID 7253. doi:10.1016/0006-291X(76)90654-9. 
  • Endo Y, Kobata A (July 1976). "Partial purification and characterization of an endo-alpha-N-acetylgalactosaminidase from the culture of medium of Diplococcus pneumoniae". J. Biochem. Tokyo. 80 (1): 1–8. PMID 9374. doi:10.1093/oxfordjournals.jbchem.a131240. 
  • Umemoto J, Bhavanandan VP, Davidson EA (1977). "Purification and properties of an endo-alpha-N-acetyl-D-galactosaminidase from Diplococcus pneumoniae". J. Biol. Chem. 252 (23): 8609–14. PMID 21877.