Mucrocetin

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mucrocetin, subunit A
1v4l.jpg
Mucrocetin hetero24mer (A+B)
Identifiers
OrganismProtobothrops mucrosquamatus
Symbol?
PDB1v4l (ECOD)
UniProtQ6TPH0
mucrocetin, subunit B
Identifiers
OrganismProtobothrops mucrosquamatus
Symbol?
PDB1v4l (ECOD)
UniProtQ6TPG9

Mucrocetin is a snake venom platelet-agglutinating factor, that acts in a vWF-independent manner. It binds specifically to platelet GPIbalpha (GP1BA) to a distinct binding site from that of flavocetin-A. It is isolated from the venom of Taiwan habu (Protobothrops mucrosquamatus).[1]

It is related to the C-type lectins.

References[edit]

  1. ^ Huang KF, Ko TP, Hung CC, Chu J, Wang AH, Chiou SH (March 2004). "Crystal structure of a platelet-agglutinating factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus)". The Biochemical Journal. 378 (Pt 2): 399–407. doi:10.1042/BJ20031507. PMC 1223962. PMID 14613481.