Mulder's sign

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Mulder's sign
Differential diagnosisMorton's neuroma

Mulder's sign is a physical exam finding associated with Morton's neuroma, which may be elicited while the patient is in the supine position on the examination table. The pain of the neuroma, as well as a click, can be produced by squeezing the two metatarsal heads together with one hand, while concomitantly putting pressure on the interdigital space with the other hand. With this technique, the pain of the Morton's neuroma will be localized strictly to the plantar surface of the involved interspace, with paresthesias radiating into the affected toes.


It is named after the Dutch surgeon and podiatrist, Jacob D. Mulder (1901–1965).[1][2][3]


  1. ^ Mulder, Jacob D.; "The causative mechanism in Morton's metatarsalgia", Journal of Bone and Joint Surgery 1951, 33B (British volume), pp. 94-95
  2. ^ Bencardino, Jenny; Rosenberg, Zehava S.; Beltran, Javier; Liu, Xiang; and Marty-Delfaut, Emmanuelle; "Morton's Neuroma: Is It Always Symptomatic?" American Journal of Roentgenology, September 2000, vol. 175, no. 3, pp. 649-653
  3. ^ "The Mulder Test for Morton Neuroma" Archived 2006-11-01 at the Wayback Machine, in Waldman, Steven; Physical Diagnosis of Pain, Saunders, October 2005, p. 381, ISBN 1-4160-0112-3