It recounts the daily lives of the widowed Countess of Ludlow of Hanbury and the spinster Miss Galindo, whose father was a Baronet, and their caring for other single women and girls. It is also concerned with Lady Ludlow's man of business, Mr Horner, and a poacher's son named Harry Gregson whose education he provides for.
With Cranford, The Last Generation in England and Mr. Harrison's Confessions, My Lady Ludlow was adapted for television in 2007 as Cranford, with Francesca Annis as the eponymous character, with Alex Etel as Harry Gregson and Emma Fielding as Laurentia Galindo. Mr Horner's name was changed to Mr Carter, and was played by Philip Glenister. The character of Lord Septimus, the Countess' seventh child, is mentioned in the first series as he is in the novella. The book, however, was extended in the first episode of the second series Return to Cranford, featuring the death of Lady Ludlow from bone cancer, and Lord Septimus' return from Italy to claim his estate, where his ne'er-do-well personality is revealed. In the episode, Lord Septimus was portrayed by Rory Kinnear, with Annis, Etel and Fielding reprising their roles.