Mycoplasma hominis

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Mycoplasma hominis
Scientific classification
M. hominis
Binomial name
Mycoplasma hominis
(Freundt 1953)
Edward 1955

Mycoplasma hominis is a species of bacteria in the genus Mycoplasma. M. hominis has the ability to penetrate the interior of human cells.[1] Along with ureaplasmas, mycoplasmas are the smallest free-living organisms known.

They have no cell wall and therefore do not Gram stain.

M. hominis is associated with pelvic inflammatory disease[2][3] and bacterial vaginosis.[4] It is also associated with male infertility.[5] This species causes a sexually transmitted disease.[6] It is susceptible to the antibiotic clindamycin.[7]

Growth of "fried egg" colonies on glucose agar medium within 24–48 hours is a characteristic of Mycoplasma hominis.

Genome studies[edit]

DNA sequence data is incomplete for M. hominis. M. hominis uses an atypical type of energy metabolism, dependent upon the degradation of arginine. Other mycoplasmas lack this characteristic. Determining the genome will provide information that would facilitate the understanding of metabolic reconstitutions.[8]

See also[edit]


  1. ^ "Mycoplasma hominis PG21". Site du Genoscope. 2013-10-19. Retrieved 2015-08-30.
  2. ^ Taylor-Robinson, D (Oct 1996). "Infections due to species of Mycoplasma and Ureaplasma: an update". Clin Infect Dis. 23 (4): 671–82. doi:10.1093/clinids/23.4.671. PMID 8909826.
  3. ^ Ljubin-Sternak, Suncanica; Mestrovic, Tomislav (2014). "Review: Clamydia trachomatis and Genital Mycoplasmias: Pathogens with an Impact on Human Reproductive Health". Journal of Pathogens. 2014 (183167): 183167. doi:10.1155/2014/183167. PMC 4295611. PMID 25614838.
  4. ^ Mastromarino, Paola; Vitali, Beatrice; Mosca, Luciana (2013). "Bacterial vaginosis: a review on clinical trials with probiotics" (PDF). New Microbiologica. 36 (3): 229–238. PMID 23912864.
  5. ^ C. Huang; H.L. Zhu; K.R. Xu; S.Y. Wang; L.Q. Fan; W.B. Zhu (September 2015). "Mycoplasma and ureaplasma infection and male infertility: a systematic review and meta-analysis". Andrology. 3 (5): 809–816. doi:10.1111/andr.12078. PMID 26311339.
  6. ^ Sternak, p. 1.
  7. ^ "Clindamycin" (PDF). FA Davis Company. 2017. Retrieved 15 December 2017.
  8. ^ "Mycoplasma hominis PG21". Site du Genoscope. 2013-10-19. Retrieved 2015-08-30.

Further reading[edit]

  • Song, Tiejun; Ye, Aiqing; Xie, Xinyou; Huang, Jun; Ruan, Zhi; Kong, Yingying; Song, Jingjuan; Wang, Yue; Chen, Jianzhong; Zhang, Jun (September 2014). "Epidemiological investigation and antimicrobial susceptibility analysis of ureaplasma species and Mycoplasma hominis in outpatients with genital manifestations". Journal of Clinical Pathology. 67 (9): 817–820. doi:10.1136/jclinpath-2014-202248. PMID 24982440.
  • Hasebe, Akira; Mu, Hong-Hua; Cole, Barry C (September 2014). "A Potential Pathogenic Factor from Mycoplasma hominisis a TLR2-Dependent, Macrophage-Activating, P50-Related Adhesin". American Journal of Reproductive Immunology. 72 (3): 285–295. doi:10.1111/aji.12279. hdl:2115/59366. PMID 24938999.
  • Pignanelli S, Pulcrano G, Schiavone P, Iula VD, Catania MR. In vitro antimicrobial susceptibility of Mycoplasma hominis genital isolates. Indian J Dermatol Venereol Leprol. 2015 May-Jun;81(3):286-8. doi: 10.4103/0378-6323.153520.

External links[edit]