Myelin-associated glycoprotein

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MAG
Identifiers
Aliases MAG, GMA, S-SIGLEC-4A, SIGLEC4A, SPG75, myelin associated glycoprotein
External IDs OMIM: 159460 MGI: 96912 HomoloGene: 1771 GeneCards: MAG
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080600
NM_001199216
NM_002361

NM_010758

RefSeq (protein)

NP_001186145
NP_002352
NP_542167

Location (UCSC) Chr 19: 35.29 – 35.31 Mb Chr 7: 30.9 – 30.91 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse
myelin associated glycoprotein
Identifiers
Symbol MAG
Alt. symbols GMA
Entrez 4099
HUGO 6783
OMIM 159460
RefSeq NM_080600
UniProt P20916
Other data
Locus Chr. 19 q13.1

Myelin-associated glycoprotein (MAG, Siglec-4) is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR.[3] MAG is believed to be involved in myelination during nerve regeneration.[4]

See also[edit]

External links[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Quarles RH (2007). "Myelin-associated glycoprotein (MAG): past, present and beyond". Journal of Neurochemistry. 100 (6): 1431–48. doi:10.1111/j.1471-4159.2006.04319.x. PMID 17241126. 
  4. ^ Barton D, Arquint M, Roder J, Dunn R, Francke U (1987). "The myelin-associated glycoprotein gene: mapping to human chromosome 19 and mouse chromosome 7 and expression in quivering mice". Genomics. 1 (2): 107–12. doi:10.1016/0888-7543(87)90002-4. PMID 2447011.