Myelin-associated glycoprotein

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MAG
Identifiers
AliasesMAG, GMA, S-SIGLEC-4A, SIGLEC4A, SPG75, myelin associated glycoprotein
External IDsOMIM: 159460 MGI: 96912 HomoloGene: 1771 GeneCards: MAG
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for MAG
Genomic location for MAG
Band19q13.12Start35,292,125 bp[1]
End35,313,804 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080600
NM_001199216
NM_002361

NM_010758

RefSeq (protein)

NP_001186145
NP_002352
NP_542167

Location (UCSC)Chr 19: 35.29 – 35.31 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse
myelin associated glycoprotein
Identifiers
Symbol MAG
Alt. symbols GMA
Entrez 4099
HUGO 6783
OMIM 159460
RefSeq NM_080600
UniProt P20916
Other data
Locus Chr. 19 q13.1

Myelin-associated glycoprotein (MAG, Siglec-4) is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NoGo-66 receptor, (NgR).[4] MAG is believed to be involved in myelination during nerve regeneration.[5]

See also[edit]

External links[edit]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000105695 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Quarles RH (2007). "Myelin-associated glycoprotein (MAG): past, present and beyond". Journal of Neurochemistry. 100 (6): 1431–48. doi:10.1111/j.1471-4159.2006.04319.x. PMID 17241126. 
  5. ^ Barton D, Arquint M, Roder J, Dunn R, Francke U (1987). "The myelin-associated glycoprotein gene: mapping to human chromosome 19 and mouse chromosome 7 and expression in quivering mice". Genomics. 1 (2): 107–12. doi:10.1016/0888-7543(87)90002-4. PMID 2447011.