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The term myeloid (myelogenous) is an adjective that can refer to a progenitor cell for granulocytes, monocytes, erythrocytes, or platelets.[1][2] Myeloid can be distinguished from the lymphoid progenitor cells that give rise to B cells and T cells.[2] Myleloid is thus associated with the innate immune system, in contrast to lymphoid, which is associated with the adaptive immune system. Myelogenous usually refers to nonlymphocytic white blood cells,[3] and erythroid can often be used to distinguish erythrocyte-related from myeloid and lymphoid.[4]

Myeloid cells originate in bone marrow or spinal cord, or a resemblance to the marrow or spinal cord. For example, myeloid leukemia is leukemia that arises from abnormal growth in the blood-forming tissue of the bone marrow.[5]

This term should not be confused with "myelin", which is an insulating layer covering the axons of many neurons.

Myeloid neoplasms always concern bone marrow and are related to hematopoietic cells.

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  1. ^ Kawamoto H1, Minato N (2004). "Myeloid cells". The International Journal of Biochemistry & Cell Biology 36 (8): 1374–1379. PMID 15147715. 
  2. ^ a b Orkin SH, Zon LI (2008). "Hematopoiesis: an evolving paradigm for stem cell biology". Cell 132 (4): 631–644. doi:10.1016/j.cell.2008.01.025. PMC 2628169. PMID 18295580. 
  3. ^ "Definition of Myelogenous". MedicineNet. August 28, 2013. Retrieved 2015-09-10. 
  4. ^ Yuan J, Nguyen CK, Liu X, Kanellopoulou C, Muljo SA (2012). "Lin28b reprograms adult bone marrow hematopoietic progenitors to mediate fetal-like lymphopoiesis". Science 335 (6073): 1195–1200. doi:10.1126/science.1216557. PMC 3471381. PMID 22345399. 
  5. ^ Macpherson, Gordon (2002). Black's Medical Dictionary. London: A & C Black Publishers. ISBN 978-1-56833-129-4. [page needed]

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