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Myospherulosis, also known as spherulocytosis,[1] is a foreign body-type granulomatous reaction to lipid-containing material and blood.[1][2]

It may be seen in various settings including:

The resultant histopathologic pattern is most unusual and initially was mistakenly thought to represent a previously undescribed endosporulating fungus.

See also[edit]


  1. ^ a b c Godbersen, GS.; Kleeberg, J.; Lüttges, J.; Werner, JA. (Sep 1995). "[Spherulocytosis (myospherulosis) of the paranasal sinuses].". HNO. 43 (9): 552–5. PMID 7591868. 
  2. ^ Fisher, SC.; Horning, GM.; Hellstein, JW. (Dec 2001). "Myospherulosis complicating cortical block grafting: a case report.". J Periodontol. 72 (12): 1755–9. doi:10.1902/jop.2001.72.12.1755. PMID 11811513. 
  3. ^ Chau, KY.; Pretorius, JM.; Stewart, AW. (Oct 2000). "Myospherulosis in renal cell carcinoma.". Arch Pathol Lab Med. 124 (10): 1476–9. doi:10.1043/0003-9985(2000)124<1476:MIRCC>2.0.CO;2. PMID 11035579.