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Skeletal formula of n-butylamine
Ball-and-stick model of the N-butylamine molecule
IUPAC name
Other names
  • 1-Aminobutane
  • 1-Butanamine
  • Monobutylamime
109-73-9 YesY
Abbreviations NBA
ChemSpider 7716 YesY
DrugBank DB03659 N
EC number 203-699-2
Jmol-3D images Image
MeSH n-butylamine
PubChem 8007
RTECS number EO29750002
UN number 1125
Molar mass 73.14 g·mol−1
Appearance Colorless liquid
Odor fishy, ammoniacal
Density 740 mg mL−1
Melting point −49 °C; −56 °F; 224 K
Boiling point 77 to 79 °C; 170 to 174 °F; 350 to 352 K
log P 1.056
Vapor pressure 9.1 kPa (at 20 °C)
570 μmol Pa−1 kg−1
Viscosity 500 µPa s (at 20 °C)
188 J K−1 mol−1
−128.9–−126.5 kJ mol−1
−3.0196–−3.0174 MJ mol−1
Safety data sheet hazard.com
GHS pictograms The flame pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The corrosion pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The exclamation-mark pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word DANGER
H225, H302, H312, H314, H332
P210, P280, P305+351+338, P310
EU classification Highly Flammable F Corrosive C
R-phrases R11 R20/21/22, R35
S-phrases S3, S16, S26, S29 S36/37/39 S45
NFPA 704
Flammability code 3: Liquids and solids that can be ignited under almost all ambient temperature conditions. Flash point between 23 and 38 °C (73 and 100 °F). E.g., gasoline) Health code 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g., chloroform Reactivity code 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g., liquid nitrogen Special hazards (white): no codeNFPA 704 four-colored diamond
Flash point −7 °C (19 °F; 266 K)
312 °C (594 °F; 585 K)
Explosive limits 1.7–9.8%
Lethal dose or concentration (LD, LC):
  • 366 mg kg−1 (oral, rat)
  • 626 mg kg−1 (dermal, rabbit)
  • 430 mg kg−1 (oral, mouse)
  • 430 mg kg−1 (oral, guinea pig)
4000 ppm (rat, 4 hr)
263 ppm (mouse, 2 hr)[3]
US health exposure limits (NIOSH):
C 5 ppm (15 mg/m3) [skin][2]
C 5 ppm (15 mg/m3) [skin][2]
300 ppm[2]
Related compounds
Related alkanamines
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 N verify (what isYesY/N?)
Infobox references

n-Butylamine is an organic compound (specifically, an amine) with the formula CH3CH2CH2CH2NH2. This colourless liquid is one of the four isomeric amines of butane, the others being sec-butylamine, tert-butylamine and isobutylamine. At standard temperature and pressure, n-butylamine is a liquid having the fishy, ammonia-like odor common to amines. The liquid acquires a yellow color upon storage in air. It is soluble in all organic solvents.

Like other simple, aliphatic amines, n-butylamine is a weak base, with a pKa, in its protonated form, of 10.59.[4]


This compound is used as an ingredient in the manufacture of pesticides (such as thiocarbazides), pharmaceuticals, and emulsifiers. It is also a precursor for the manufacture of N,N'-dibutylthiourea, a rubber vulcanization accelerator, and n-butylbenzenesulfonamide, a plasticizer of nylon.


The LD50 to rats through the oral exposure route is 366 mg/kg.[5]

In regards to occupational exposures to n-Butylamine, the Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits at a ceiling of 5 ppm (15 mg/m3) for dermal exposure.[6]


  1. ^ "n-butylamine - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 26 March 2005. Identification and Related Records. Retrieved 8 May 2012. 
  2. ^ a b c "NIOSH Pocket Guide to Chemical Hazards #0079". National Institute for Occupational Safety and Health (NIOSH). 
  3. ^ a b "N-Butylamine". Immediately Dangerous to Life and Health. National Institute for Occupational Safety and Health (NIOSH). 
  4. ^ H. K. Hall (1957) J. Am. Chem. Soc. 79 5441.
  5. ^ n-Butylamine MSDS
  6. ^ CDC - NIOSH Pocket Guide to Chemical Hazards