N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline

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N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline[1]
EEDQ.png
Names
IUPAC name
2-Ethoxy-2H-quinoline-1-carboxylic acid ethyl ester
Other names
Ethyl 1,2-dihydro-2-ethoxyquinoline-1-carboxylate
Identifiers
16357-59-8 YesY
Abbreviations EEDQ
Jmol 3D model Interactive image
PubChem 27833
Properties
C14H17NO3
Molar mass 247.29 g/mol
Melting point 62 to 67 °C (144 to 153 °F; 335 to 340 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) is an irreversible dopamine-receptor antagonist.[2]

EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization.[3]

References[edit]