NAPSA

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NAPSA
Identifiers
Aliases NAPSA, KAP, Kdap, NAP1, NAPA, SNAPA, napsin A aspartic peptidase
External IDs MGI: 109365 HomoloGene: 68418 GeneCards: NAPSA
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004851

NM_008437

RefSeq (protein)

NP_004842

NP_032463.1
NP_032463

Location (UCSC) Chr 19: 50.36 – 50.37 Mb Chr 7: 44.57 – 44.59 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Napsin-A is a protein that in humans is encoded by the NAPSA gene.[3]

The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus.[3]

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Further reading[edit]