NBUMP

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NBUMP
NBUMP.png
Clinical data
ATC code
  • none
Identifiers
CAS Number
PubChem CID
Chemical and physical data
FormulaC26H39N3O2
Molar mass425.607 g/mol g·mol−1
  (verify)

NBUMP is a highly selective 5-HT1A receptor partial agonist (Ki = 0.1 nM; IA = 40%) with an arylpiperazine structure.[1] It is one of the highest affinity ligands for the 5-HT1A receptor known.[1] It displays 460- and 260-fold selectivity for 5-HT1A over the α1-adrenergic and D2 receptors, respectively.[1]

See also

References

  1. ^ a b c Roth, Bryan L. (2006). The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics (The Receptors). Totowa, NJ: Humana Press. ISBN 1-58829-568-0.