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Non-SMC condensin I complex, subunit G
External IDs OMIM606280 HomoloGene44071 GeneCards: NCAPG Gene
RNA expression pattern
PBB GE NCAPG 218662 s at tn.png
PBB GE NCAPG 218663 at tn.png
More reference expression data
Species Human Mouse
Entrez 64151 54392
Ensembl ENSG00000109805 ENSMUSG00000015880
UniProt Q9BPX3 n/a
RefSeq (mRNA) NM_022346 NM_019438
RefSeq (protein) NP_071741 NP_062311
Location (UCSC) Chr 4:
17.81 – 17.84 Mb
Chr 5:
45.67 – 45.7 Mb
PubMed search [1] [2]

Condensin complex subunit 3 also known as condensin subunit CAP-G (CAP-G) or non-SMC condensin I complex subunit G (NCAPG) is a protein that in humans is encoded by the NCAPG gene.[1][2][3] CAP-G is a subunit of condensin I, a large protein complex involved in chromosome condensation.


NCAPG has been shown to interact with DNMT3B.[4]


  1. ^ Jäger D, Stockert E, Jäger E, Güre AO, Scanlan MJ, Knuth A, Old LJ, Chen YT (Aug 2000). "Serological cloning of a melanocyte rab guanosine 5'-triphosphate-binding protein and a chromosome condensation protein from a melanoma complementary DNA library". Cancer Res. 60 (13): 3584–91. PMID 10910072. 
  2. ^ Kimura K, Cuvier O, Hirano T (Feb 2001). "Chromosome condensation by a human condensin complex in Xenopus egg extracts". J. Biol. Chem. 276 (8): 5417–20. doi:10.1074/jbc.C000873200. PMID 11136719. 
  3. ^ "Entrez Gene: NCAPG non-SMC condensin I complex, subunit G". 
  4. ^ Geiman TM, Sankpal UT, Robertson AK, Chen Y, Mazumdar M, Heale JT, Schmiesing JA, Kim W, Yokomori K, Zhao Y, Robertson KD (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Res. 32 (9): 2716–29. doi:10.1093/nar/gkh589. PMC 419596. PMID 15148359. 

Further reading[edit]