NDST2

NDST2
Identifiers
Aliases	NDST2, HSST2, NST2, N-deacetylase/N-sulfotransferase 2, N-deacetylase and N-sulfotransferase 2, N-HSST 2
External IDs	OMIM: 603268; MGI: 97040; HomoloGene: 20803; GeneCards: NDST2; OMA:NDST2 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	73,811,798 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	20,784,630 bp
RNA expression pattern
	Top expressed in
	spleen; ; granulocyte; ; blood; ; bone marrow; ; tonsil; ; right hemisphere of cerebellum; ; gastric mucosa; ; minor salivary glands; ; sural nerve; ; appendix;
	Top expressed in
	neural layer of retina; ; granulocyte; ; dermis; ; lip; ; ankle joint; ; ventricular zone; ; yolk sac; ; tail of embryo; ; spermatocyte; ; decidua;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; sulfotransferase activity; catalytic activity; hydrolase activity; N-acetylglucosamine deacetylase activity; [heparan sulfate-glucosamine N-sulfotransferase activity]; deacetylase activity; heparan sulfate sulfotransferase activity; heparan sulfate N-acetylglucosaminyltransferase activity;
Cellular component	integral component of membrane; Golgi membrane; Golgi apparatus; membrane;
Biological process	metabolism; heparan sulfate proteoglycan biosynthetic process; heparin biosynthetic process; glycosaminoglycan biosynthetic process; regulation of angiotensin levels in blood; cellular process; sulfur compound metabolic process; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	8509
	17423
	ENSG00000166507
	ENSMUSG00000039308
	P52849
	P52850
	NM_001330107; NM_003635
	NM_010811
	NP_001317036; NP_003626
	NP_034941
	Wikidata
View/Edit Human	View/Edit Mouse

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 is an enzyme that in humans is encoded by the NDST2 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166507 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000039308 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Humphries DE, Lanciotti J, Karlinsky JB (Jul 1998). "cDNA cloning, genomic organization and chromosomal localization of human heparan glucosaminyl N-deacetylase/N-sulphotransferase-2". Biochem J. 332 (2): 303–7. PMC 1219482. PMID 9601056.
^ "Entrez Gene: NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2".

References

Further reading