From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Legal status
Legal status
CAS Number
PubChem CID
Chemical and physical data
Molar mass367.492 g·mol−1
3D model (JSmol)

NE-CHMIMO (CHM-018) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug.[1][2][3] NE-CHMIMO is the 1-cyclohexylmethyl (instead of 1-pentyl) analogue of the first-generation synthetic cannabinoid JWH-018. The corresponding cyclohexylmethyl derivative of JWH-081 had also been reported several months earlier.[4]

Legal status[edit]

In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)indole class such as NE-CHMIMO are Schedule I Controlled Substances.[5]

NE-CHMIMO is a controlled substance in Japan as of November 2019.[6]

See also[edit]


  1. ^ Angerer, Verena; Bisel, Philippe; Moosmann, Bjoern; Westphal, Folker; Auwärter, Volker (September 2016). "Separation and structural characterization of the new synthetic cannabinoid JWH-018 cyclohexyl methyl derivative "NE-CHMIMO" using flash chromatography, GC-MS, IR and NMR spectroscopy". Forensic Science International. 266: e93–e98. doi:10.1016/j.forsciint.2016.05.031. ISSN 0379-0738. PMID 27297324.
  2. ^ Franz, Florian; Jechle, Hanna; Angerer, Verena; Pegoro, Melanie; Auwärter, Volker; Neukamm, Merja A. (May 2018). "Synthetic cannabinoids in hair – Pragmatic approach for method updates, compound prevalences and concentration ranges in authentic hair samples". Analytica Chimica Acta. 1006: 61–73. doi:10.1016/j.aca.2017.12.029. ISSN 0003-2670. PMID 30016265.
  3. ^ "NE-CHMIMO". New Synthetic Drugs Database.
  4. ^ Blakey, Karen; Boyd, Sue; Atkinson, Sarah; Wolf, Jenna; Slottje, Pim M.; Goodchild, Katrina; McGowan, Jenny (March 2016). "Identification of the novel synthetic cannabimimetic 8-quinolinyl 4-methyl-3-(1-piperidinylsulfonyl)benzoate (QMPSB) and other designer drugs in herbal incense". Forensic Science International. 260: 40–53. doi:10.1016/j.forsciint.2015.12.001. ISSN 0379-0738. PMID 26795397.
  5. ^ 21 U.S.C. § 812: Schedules of controlled substances
  6. ^ "指定薬物を指定する省令が公布されました|厚生労働省". (in Japanese). Ministry of Health, Labour and Welfare. Retrieved 2019-12-22.