NETO1

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NETO1
Identifiers
Aliases NETO1, BCTL1, BTCL1, neuropilin and tolloid like 1
External IDs MGI: 2180216 HomoloGene: 16367 GeneCards: NETO1
Gene location (Human)
Chromosome 18 (human)
Chr. Chromosome 18 (human)[1]
Chromosome 18 (human)
Genomic location for NETO1
Genomic location for NETO1
Band 18q22.3 Start 72,742,314 bp[1]
End 72,868,146 bp[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_144946

RefSeq (protein)

NP_659195

Location (UCSC) Chr 18: 72.74 – 72.87 Mb Chr 18: 86.39 – 86.5 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Neuropilin (NRP) and tolloid (TLL)-like 1 is a protein that in humans is encoded by the NETO1 gene.[5]

Function[edit]

This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in mice encodes a protein that plays a critical role in spatial learning and memory by regulating the function of synaptic N-methyl-D-aspartic acid receptor complexes in the hippocampus. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.