NEU4

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Sialidase 4
Identifiers
Symbols NEU4 ; FLJ35928; MGC102757; MGC18222
External IDs OMIM608527 MGI2661364 HomoloGene15433 ChEMBL: 4174 GeneCards: NEU4 Gene
EC number 3.2.1.18
Orthologs
Species Human Mouse
Entrez 129807 241159
Ensembl ENSG00000204099 ENSMUSG00000034000
UniProt Q8WWR8 Q8BZL1
RefSeq (mRNA) NM_001167599.1 NM_173772.3
RefSeq (protein) NP_001161071.1 NP_776133.1
Location (UCSC) Chr 2:
242.75 – 242.76 Mb
Chr 1:
95.92 – 95.92 Mb
PubMed search [1] [2]

Sialidase-4 is an enzyme that in humans is encoded by the NEU4 gene.[1]

Function[edit]

This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids.[1]

Interactions[edit]

NEU4 has been shown to interact with PLSCR1.[2]

References[edit]

  1. ^ a b "Entrez Gene: NEU4 sialidase 4". 
  2. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

Further reading[edit]