NEU4

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NEU4
Identifiers
Aliases NEU4, neuraminidase 4
External IDs MGI: 2661364 HomoloGene: 15433 GeneCards: NEU4
Gene location (Human)
Chromosome 2 (human)
Chr. Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for NEU4
Genomic location for NEU4
Band 2q37.3 Start 241,808,825 bp[1]
End 241,817,413 bp[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_080741
NM_001167599
NM_001167600
NM_001167601
NM_001167602

NM_173772
NM_001310769

RefSeq (protein)

NP_001297698
NP_776133

Location (UCSC) Chr 2: 241.81 – 241.82 Mb Chr 2: 94.02 – 94.03 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Sialidase-4 is an enzyme that in humans is encoded by the NEU4 gene.[5]

Function[edit]

This gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids.[5]

Interactions[edit]

NEU4 has been shown to interact with PLSCR1.[6]

References[edit]

  1. ^ a b c ENSG00000277926 GRCh38: Ensembl release 89: ENSG00000204099, ENSG00000277926 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000034000 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ a b "Entrez Gene: NEU4 sialidase 4". 
  6. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

Further reading[edit]