NE1 or NE-1 may refer to:
- HarbourFront MRT Station, Singapore
- National Expressway 1 (India)
- NE1fm, a radio station in Newcastle upon Tyne, England
- Nebraska Highway 1
- Nebraska's 1st congressional district
- New England Interstate Route 1, now U.S. Route 1
- Piper NE-1, a version of the J-3 Cub for the U.S. Navy
- Royal Aircraft Factory N.E.1, a prototype aircraft of the First World War
- NE1, a postcode district in Newcastle upon Tyne, England; see NE postcode area
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