NFIA

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NFIA
Identifiers
Aliases NFIA, CTF, NF-I/A, NF1-A, NFI-A, NFI-L, nuclear factor I A, BRMUTD
External IDs MGI: 108056 HomoloGene: 4086 GeneCards: NFIA
Gene location (Human)
Chromosome 1 (human)
Chr. Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for NFIA
Genomic location for NFIA
Band 1p31.3 Start 60,865,259 bp[1]
End 61,462,793 bp[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001134673
NM_001145511
NM_001145512
NM_005595

NM_001122952
NM_001122953
NM_010905

RefSeq (protein)

NP_001128145
NP_001138983
NP_001138984
NP_005586

NP_001116424
NP_001116425
NP_035035

Location (UCSC) Chr 1: 60.87 – 61.46 Mb Chr 1: 97.77 – 98.12 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Nuclear factor 1 A-type is a protein that in humans is encoded by the NFIA gene.[5][6]

Function[edit]

Nuclear factor I (NFI) proteins constitute a family of dimeric DNA-binding proteins with similar, and possibly identical, DNA-binding specificity. They function as cellular transcription factors and as replication factors for adenovirus DNA replication. Diversity in this protein family is generated by multiple genes, differential splicing, and heterodimerization.[supplied by OMIM][6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162599 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028565 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Qian F, Kruse U, Lichter P, Sippel AE (July 1995). "Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH". Genomics. 28 (1): 66–73. doi:10.1006/geno.1995.1107. PMID 7590749. 
  6. ^ a b "Entrez Gene: NFIA nuclear factor I/A". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.