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Nuclear factor I/A
Symbols NFIA ; CTF; NF-I/A; NF1-A; NFI-A; NFI-L
External IDs OMIM600727 MGI108056 HomoloGene4086 GeneCards: NFIA Gene
Species Human Mouse
Entrez 4774 18027
Ensembl ENSG00000162599 ENSMUSG00000028565
UniProt Q12857 Q02780
RefSeq (mRNA) NM_001134673 NM_001122952
RefSeq (protein) NP_001128145 NP_001116424
Location (UCSC) Chr 1:
60.87 – 61.46 Mb
Chr 4:
97.77 – 98.12 Mb
PubMed search [1] [2]

Nuclear factor 1 A-type is a protein that in humans is encoded by the NFIA gene.[1][2]

Nuclear factor I (NFI) proteins constitute a family of dimeric DNA-binding proteins with similar, and possibly identical, DNA-binding specificity. They function as cellular transcription factors and as replication factors for adenovirus DNA replication. Diversity in this protein family is generated by multiple genes, differential splicing, and heterodimerization.[supplied by OMIM][2]


  1. ^ Qian F, Kruse U, Lichter P, Sippel AE (Dec 1995). "Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH". Genomics 28 (1): 66–73. doi:10.1006/geno.1995.1107. PMID 7590749. 
  2. ^ a b "Entrez Gene: NFIA nuclear factor I/A". 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.