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Nuclear factor, interleukin 3 regulated
Symbols NFIL3 ; E4BP4; IL3BP1; NF-IL3A; NFIL3A
External IDs OMIM605327 MGI109495 HomoloGene3928 GeneCards: NFIL3 Gene
RNA expression pattern
PBB GE NFIL3 203574 at tn.png
More reference expression data
Species Human Mouse
Entrez 4783 18030
Ensembl ENSG00000165030 ENSMUSG00000056749
UniProt Q16649 O08750
RefSeq (mRNA) NM_001289999 NM_017373
RefSeq (protein) NP_001276928 NP_059069
Location (UCSC) Chr 9:
91.41 – 91.42 Mb
Chr 13:
52.97 – 52.98 Mb
PubMed search [1] [2]

Nuclear factor, interleukin 3 regulated, also known as NFIL3 or E4BP4 is a protein which in humans is encoded by the NFIL3 gene.[1]


Expression of interleukin-3 (IL3) is restricted to activated T cells, natural killer (NK) cells, and mast cell lines. Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site.[1][2]


Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.