NHLH1

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NHLH1
Identifiers
Aliases NHLH1, HEN1, NSCL, NSCL1, bHLHa35, nescient helix-loop-helix 1
External IDs MGI: 98481 HomoloGene: 4089 GeneCards: NHLH1
Gene location (Human)
Chromosome 1 (human)
Chr. Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for NHLH1
Genomic location for NHLH1
Band 1q23.2 Start 160,367,067 bp[1]
End 160,372,848 bp[1]
RNA expression pattern
PBB GE NHLH1 214628 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005598

NM_010916

RefSeq (protein)

NP_005589
NP_005589.1

NP_035046

Location (UCSC) Chr 1: 160.37 – 160.37 Mb Chr 1: 172.05 – 172.06 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Helix-loop-helix protein 1 is a protein that in humans is encoded by the NHLH1 gene.[5]

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).[supplied by OMIM][5]

References[edit]

Further reading[edit]