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NK2 homeobox 3
Symbols NKX2-3 ; CSX3; NK2.3; NKX2.3; NKX2C; NKX4-3
External IDs OMIM606727 MGI97348 HomoloGene17061 GeneCards: NKX2-3 Gene
Species Human Mouse
Entrez 159296 18089
Ensembl ENSG00000119919 ENSMUSG00000044220
UniProt Q8TAU0 P97334
RefSeq (mRNA) NM_145285 NM_008699
RefSeq (protein) NP_660328 NP_032725
Location (UCSC) Chr 10:
99.53 – 99.54 Mb
Chr 19:
43.61 – 43.62 Mb
PubMed search [1] [2]

Homeobox protein Nkx-2.3 is a protein that in humans is encoded by the NKX2-3 gene.[1][2][3]

NKX2C is a member of the NKX family of homeodomain-containing transcription factors, which are implicated in many aspects of cell type specification and maintenance of differentiated tissue functions.[3]


  1. ^ Price M, Lazzaro D, Pohl T, Mattei MG, Ruther U, Olivo JC, Duboule D, Di Lauro R (Mar 1992). "Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain". Neuron 8 (2): 241–55. doi:10.1016/0896-6273(92)90291-K. PMID 1346742. 
  2. ^ Pabst O, Schneider A, Brand T, Arnold HH (Jul 1997). "The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- and postnatal mouse development". Dev Dyn 209 (1): 29–35. doi:10.1002/(SICI)1097-0177(199705)209:1<29::AID-AJA3>3.0.CO;2-Z. PMID 9142493. 
  3. ^ a b "Entrez Gene: NKX2-3 NK2 transcription factor related, locus 3 (Drosophila)". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.