NKX2-3

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NKX2-3
Identifiers
AliasesNKX2-3, CSX3, NK2.3, NKX2.3, NKX2C, NKX4-3, NK2 homeobox 3
External IDsMGI: 97348 HomoloGene: 17061 GeneCards: NKX2-3
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for NKX2-3
Genomic location for NKX2-3
Band10q24.2Start99,532,942 bp[1]
End99,536,524 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_145285

NM_008699

RefSeq (protein)

NP_660328

NP_032725

Location (UCSC)Chr 10: 99.53 – 99.54 MbChr 19: 43.61 – 43.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Homeobox protein Nkx-2.3 is a protein that in humans is encoded by the NKX2-3 gene.[5][6][7]

NKX2C is a member of the NKX family of homeodomain-containing transcription factors, which are implicated in many aspects of cell type specification and maintenance of differentiated tissue functions.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000119919 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044220 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Price M, Lazzaro D, Pohl T, Mattei MG, Ruther U, Olivo JC, Duboule D, Di Lauro R (Mar 1992). "Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain". Neuron. 8 (2): 241–55. doi:10.1016/0896-6273(92)90291-K. PMID 1346742.
  6. ^ Pabst O, Schneider A, Brand T, Arnold HH (Jul 1997). "The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- and postnatal mouse development". Dev Dyn. 209 (1): 29–35. doi:10.1002/(SICI)1097-0177(199705)209:1<29::AID-AJA3>3.0.CO;2-Z. PMID 9142493.
  7. ^ a b "Entrez Gene: NKX2-3 NK2 transcription factor related, locus 3 (Drosophila)".

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.