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Protein NME3 PDB 1zs6.png
Available structures
PDB Ortholog search: PDBe RCSB
Aliases NME3, DR-nm23, NDPK-C, NDPKC, NM23-H3, NM23H3, c371H6.2, NME/NM23 nucleoside diphosphate kinase 3
External IDs MGI: 1930182 HomoloGene: 20562 GeneCards: NME3
Gene location (Human)
Chromosome 16 (human)
Chr. Chromosome 16 (human)[1]
Chromosome 16 (human)
Genomic location for NME3
Genomic location for NME3
Band 16p13.3 Start 1,770,286 bp[1]
End 1,771,730 bp[1]
RNA expression pattern
PBB GE NME3 204862 s at fs.png
More reference expression data
Species Human Mouse
RefSeq (mRNA)



RefSeq (protein)



Location (UCSC) Chr 16: 1.77 – 1.77 Mb Chr 16: 24.9 – 24.9 Mb
PubMed search [3] [4]
View/Edit Human View/Edit Mouse

Nucleoside diphosphate kinase 3 is an enzyme that in humans is encoded by the NME3 gene.[5][6]


NME3 has been shown to interact with NME1[7][8] and NME2.[8][9]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000103024 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000073435 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Martinez R, Venturelli D, Perrotti D, Veronese ML, Kastury K, Druck T, Huebner K, Calabretta B (April 1997). "Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of the nm23 gene family". Cancer Res. 57 (6): 1180–7. PMID 9067290. 
  6. ^ "Entrez Gene: NME3 non-metastatic cells 3, protein expressed in". 
  7. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. PMID 16189514. doi:10.1038/nature04209. 
  8. ^ a b Negroni A, Venturelli D, Tanno B, Amendola R, Ransac S, Cesi V, Calabretta B, Raschellà G (September 2000). "Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis". Cell Death Differ. 7 (9): 843–50. PMID 11042679. doi:10.1038/sj.cdd.4400720. 
  9. ^ Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (September 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. PMID 16169070. doi:10.1016/j.cell.2005.08.029. 

Further reading[edit]