NUDT6

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NUDT6
Protein NUDT6 PDB 3FXT.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases NUDT6, ASFGF2, FGF-AS, FGF2AS, GFG-1, GFG1, nudix hydrolase 6
External IDs MGI: 2387618 HomoloGene: 31425 GeneCards: NUDT6
RNA expression pattern
PBB GE NUDT6 220183 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_198041
NM_007083

NM_001291044
NM_153561

RefSeq (protein)

NP_009014
NP_932158

NP_705789.1
NP_001277973
NP_705789

Location (UCSC) Chr 4: 122.89 – 122.92 Mb Chr 3: 37.4 – 37.42 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Nucleoside diphosphate-linked moiety X motif 6 is a protein that in humans is encoded by the NUDT6 gene.[3][4][5]

FGF2 (MIM 134920) is a highly conserved, multifunctional heparin-binding growth factor involved in neuroectoderm development, angiogenesis, and wound healing. Elevated levels of FGF2 are associated with proliferation of smooth muscle in atherosclerosis and with proliferation of tumors. The FGF2 antisense gene, NUDT6, may regulate FGF2 expression.[supplied by OMIM][5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Murphy PR, Knee RS (Jan 1995). "Identification and characterization of an antisense RNA transcript (gfg) from the human basic fibroblast growth factor gene". Mol Endocrinol. 8 (7): 852–9. doi:10.1210/me.8.7.852. PMID 7984147. 
  4. ^ Gagnon ML, Moy GK, Klagsbrun M (Apr 1999). "Characterization of the promoter for the human antisense fibroblast growth factor-2 gene; regulation by Ets in Jurkat T cells". J Cell Biochem. 72 (4): 492–506. doi:10.1002/(SICI)1097-4644(19990315)72:4<492::AID-JCB5>3.0.CO;2-H. PMID 10022609. 
  5. ^ a b "Entrez Gene: NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6". 

Further reading[edit]