Nucleoporin 155

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NUP155
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesNUP155, ATFB15, N155, nucleoporin 155kDa, nucleoporin 155
External IDsOMIM: 606694 MGI: 2181182 HomoloGene: 43155 GeneCards: NUP155
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Chromosome 5 (human)
Genomic location for NUP155
Genomic location for NUP155
Band5p13.2Start37,288,137 bp[1]
End37,371,106 bp[1]
RNA expression pattern
PBB GE NUP155 206550 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278312
NM_004298
NM_153485

NM_133227

RefSeq (protein)

NP_001265241
NP_004289
NP_705618

NP_573490

Location (UCSC)Chr 5: 37.29 – 37.37 MbChr 15: 8.11 – 8.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nucleoporin 155 (Nup155) is a protein that in humans is encoded by the NUP155 gene.[5][6]

Nucleoporins are the main components of the nuclear pore complex (NPC) of eukaryotic cells. They are involved in the bidirectional trafficking of molecules, especially mRNAs and proteins, between the nucleus and the cytoplasm. The protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. Two protein isoforms are encoded by transcript variants of this gene.[6]

Interactions[edit]

NUP155 has been shown to interact with GLE1L.[7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000113569 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022142 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhang X, Yang H, Corydon MJ, Zhang X, Pedersen S, Korenberg JR, Chen XN, Laporte J, Gregersen N, Niebuhr E, Liu G, Bolund L (Jun 1999). "Localization of a human nucleoporin 155 gene (NUP155) to the 5p13 region and cloning of its cDNA". Genomics. 57 (1): 144–51. doi:10.1006/geno.1999.5741. PMID 10191094.
  6. ^ a b "Entrez Gene: NUP155 nucleoporin 155kDa".
  7. ^ Rayala, Heidi J; Kendirgi Frederic; Barry Dianne M; Majerus Philip W; Wente Susan R (Feb 2004). "The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155". Mol. Cell. Proteomics. United States. 3 (2): 145–55. doi:10.1074/mcp.M300106-MCP200. ISSN 1535-9476. PMID 14645504.

Further reading[edit]