Nucleoporin 205

From Wikipedia, the free encyclopedia
  (Redirected from NUP205)
Jump to: navigation, search
NUP205
Available structures
PDB Human UniProt search: PDBe RCSB
Identifiers
Aliases NUP205, C7orf14, NPHS13, nucleoporin 205kDa, nucleoporin 205
External IDs MGI: 2141625 HomoloGene: 45971 GeneCards: NUP205
Genetically Related Diseases
mammary Paget's disease[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_015135
NM_001329434

NM_027513

RefSeq (protein)

NP_001316363
NP_055950

n/a

Location (UCSC) Chr 7: 135.56 – 135.65 Mb Chr 6: 35.18 – 35.25 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Nucleoporin 205 (Nup205) is a protein that in humans is encoded by the NUP205 gene.[4][5][6]

Function[edit]

Transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPC's are composed of subcomplexes, and NUP205 is part of one such subcomplex.[4]

References[edit]

  1. ^ "Diseases that are genetically associated with NUP205 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ a b "Entrez Gene: NUP205 nucleoporin 205kDa". 
  5. ^ Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (October 1996). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502. 
  6. ^ Grandi P, Dang T, Pané N, Shevchenko A, Mann M, Forbes D, Hurt E (October 1997). "Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly". Mol. Biol. Cell. 8 (10): 2017–38. doi:10.1091/mbc.8.10.2017. PMC 25664Freely accessible. PMID 9348540. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.