The Nansemond River is a 19.8-mile-long (31.9 km) tributary of the James River in Virginia in the United States. English settlers named the river for the Nansemond tribe of Native Americans, who then inhabited the area. The river begins at the outlet of Lake Meade north of downtown Suffolk, historically marking the northern boundary of the city. The Nansemond River Light once marked the river's confluence with the James.
The Nansemond National Wildlife Refuge is located along the river.
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