A lower or higher than average nasal bridge can be a sign of various genetic disorders, such as fetal alcohol syndrome. A flat nasal bridge can be a sign of Down syndrome (Trisomy 21), Fragile X syndrome, 48,XXXY variant Klinefelter syndrome or fetal alcohol syndrome.
An appearance of a widened nasal bridge can be seen with dystopia canthorum, which is a lateral displacement of the inner canthi of the eyes. Dystopia canthorum is associated with Waardenburg syndrome.
- Montagu, A. (1989) Growing Young N.Y.: McGraw Hill pp. 40
- Klinefelter Syndrome Clinical Presentation
- Genetic Hearing Loss Archived 2013-02-17 at the Wayback Machine. from UTMB, Dept. of Otolaryngology. DATE: March 17, 2004. RESIDENT PHYSICIAN: Jing Shen. FACULTY PHYSICIAN: Ronald W. Deskin, MD. SERIES EDITORS: Francis B. Quinn, Jr., MD and Matthew W. Ryan, MD.
- Tagra S, Talwar AK, Walia RL, Sidhu P (2006). "Waardenburg syndrome". Indian J Dermatol Venereol Leprol. 72 (4): 326. doi:10.4103/0378-6323.26718. PMID 16880590.
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