Nasal septum perforation

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Nasal septum perforation
Septal Perforation.jpg
Classification and external resources
Specialty pulmonology
ICD-10 J34.8
ICD-9-CM 478.1

A nasal septum perforation is a medical condition in which the nasal septum, the cartilaginous membrane dividing the nostrils, develops a hole or fissure.

This may be brought on directly, as in the case of nasal piercings, or indirectly, as by long-term topical drug application, including intranasal ethylphenidate, methamphetamine, cocaine, crushed prescription pills, or decongestant nasal sprays, chronic epistaxis and as a complication of nasal surgery like septoplasty or rhinoplasty. Much less common causes for perforated nasal septums include rare granulomatous inflammatory conditions like granulomatosis with polyangiitis. It has been reported as a side effect of anti-angiogenesis drugs like bevacizumab.

Signs and symptoms[edit]

A perforated septum can vary in size and location, and is usually found deep inside the nose. It may be asymptomatic, or cause a variety of signs and symptoms. Small perforations can cause a whistling noise when breathing. Larger perforations usually have more severe symptoms. These can be a combination of crusting, blood discharge, difficulty breathing, nasal pressure and discomfort. The closer the perforation is to the nostrils, the more likely it is to cause symptoms.


The majority of septal perforations can be managed without surgery. The hole will never close but if the open, raw trailing edge of the perforation can heal, the vast majority of symptoms resolve. The open irritated and raw surface must be continuously covered with a cream using a cotton applicator. This will prevent this area from drying out, cracking, bleeding, forming a scab and crusting up. A few months of successful application will allow the ulcerated edge to heal and reduces or resolves symptoms.

In a small percentage of patients surgery is necessary to alleviate symptoms.[1] There are several different surgical procedures with reported success rates between 40 and 95%. Often these can't be reproduced by other surgeons which suggests the actual rate is lower.

See also[edit]


  1. ^ Palaoucci (April 2006). "Surgical Treatment for Nasal septum perforation". Acta Otorhinolaryngol Ital 26 (2): 102–9. PMC 2639981. PMID 16886852. 

External links[edit]