From Wikipedia, the free encyclopedia
Jump to navigation Jump to search
Russell 2000 Component
IndustryGenetic testing
HeadquartersSan Carlos, California
Key people
Steve Chapman (CEO) Jonathan Sheena (CTO) Matthew Rabinowitz (Executive Chairman)
RevenueIncrease US$ 210.9 million (2017)

Natera (previously Gene Security Network) is a genetic testing company that operates a CLIA-certified laboratory in San Carlos, California.[1] The company specializes in analyzing microscopic quantities of DNA for reproductive health indications to provide preconception and prenatal genetic testing services primarily to OBGYN physicians and in vitro fertilization centers.[2]

In early 2013, the company launched Panorama, a non-invasive prenatal test for pregnant women that screens for the most common chromosomal anomalies in a fetus as early as nine weeks of gestation.[3] Other services include tests for preimplantation genetic diagnosis (PGD) and miscarriage testing to determine the cause of the loss of the pregnancy.[4] A non-invasive paternity test based on Natera’s technology, was brought to market in August 2011 through a partnership with DNA Diagnostics Center (DDC), which holds a license to the technology in the United States.[5]

In July 2015, Natera conducted an initial public offering of common stock at a price of $18.00 per share. The shares trade on the Nasdaq Global Select Market under the symbol "NTRA."[6]

Panorama Test[edit]

Natera launched a non-invasive prenatal test (NIPT) in February 2013 called Panorama that uses an advanced bioinformatics-based algorithm to analyze the cell-free fetal DNA that is found in the mother’s blood. Panorama detects chromosome abnormalities, including Trisomy 21, the cause of Down syndrome, Trisomy 18, the cause of Edwards syndrome, Trisomy 13, the cause of Patau syndrome, sex chromosome abnormalities, triploidy and certain microdeletions as early as the first trimester of pregnancy.[7][8][9] A clinical study evaluating Natera’s NIPT is funded by the National Institutes of Health and is currently ongoing.


Companies also offering non-invasive prenatal genetic testing include Sequenom, Ariosa (Harmony Prenatal Test), Ravgen, and Verinata Health. Other companies and universities that are working towards developing non-invasive prenatal testing include Stanford University,[10] Fluidigm and Ikonisys.


  1. ^ Prenatal testing company Natera raises $20M (San Francisco Business Times)
  2. ^ One-on-One with Natera founder Jonathan Sheena (San Francisco Business Times)
  3. ^ Natera Launches Noninvasive Prenatal Test; Quest to Offer in Limited Areas by March, Nationwide in April (GenomeWeb)
  4. ^ "Miscarriage Mysteries Create New Market for Natera - Xconomy". 12 February 2014.
  5. ^ "GSN Races to Improve Prenatal Tests for Genetic Conditions" – via
  6. ^ "Natera, Inc. Common Stock (NTRA) Real-Time Stock Quote -". Retrieved 2018-06-28.
  7. ^ "Innovator: Matt Rabinowitz Sifts Gene Data for Healthy Pregnancies". 26 April 2013 – via
  8. ^ Nicolaides KH, Syngelaki A, Gil MM, Quezada MS, Zinevich Y (October 2013). "Prenatal Detection of Fetal Triploidy from Cell-Free DNA Testing in Maternal Blood". Fetal Diagnosis and Therapy. 35 (3): 212–7. doi:10.1159/000355655. PMID 24135152.
  9. ^ Check Hayden, Erika (6 March 2014). "Prenatal-screening companies expand scope of DNA tests". Nature. 507 (7490): 19–19. doi:10.1038/507019a.
  10. ^ "Non-invasive prenatal test for Down's syndrome developed". BioNews.

External links[edit]