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Description neXtProt: exploring the universe of human proteins
Data types
Protein annotation
Organisms Human
Research center Swiss Institute of Bioinformatics
Laboratory CALIPHO
Primary citation Gaudet, et al. (2016)[1]
Web Search, BLAST
License Creative Commons Attribution-NoDerivs
Versioning Yes
Data release
Data: 3 to 4 times per year
Curation policy Yes - manual and automatic
Yes - individual protein entries views and searches

neXtProt is an on-line knowledge platform on human proteins. It strives to be a comprehensive resource that provides a variety of types of information on human proteins, such as their function, subcellular location, expression, interactions and role in diseases. Currently, the major part of the information in neXtProt [2] is obtained from the UniProt Swiss-Prot database but it is complemented by data originating from high-throughput studies with an emphasis on proteomics. neXtProt offers also an advanced search capacity based on the SPARQL technology as well as an API that allows to programatically extract the data stored in the resource. It is developed by the CALIPHO group[3] directed by Amos Bairoch and Lydie Lane of the Swiss Institute of Bioinformatics (SIB).


  1. ^ Gaudet, P; Michel, PA; Zahn-Zabal, M; Britan, A; Cusin, I; Domagalski, M; Duek, PD; Gateau, A; Gleizes, A; Hinard, V; de Laval, VR; Lin, J; Nikitin, F; Schaeffer, M; Teixeira, D; Lane, L; Bairoch, A (29 November 2016). "The neXtProt knowledgebase on human proteins: 2017 update.". Nucleic acids research. PMID 27899619. 
  2. ^ Lane Lydie (2012). "neXtProt: a knowledge platform for human proteins". Nucleic Acids Research. 40 (Database issue): D76–D83. PMC 3245017Freely accessible. PMID 22139911. doi:10.1093/nar/gkr1179. 
  3. ^ CALIPHO group, on the web site of the SIB

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