Nedaplatin

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Nedaplatin
Nedaplatin.png
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
IV
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
UNII
KEGG
Chemical and physical data
Formula C2H8N2O3Pt
Molar mass 303.17 g/mol
3D model (Jmol)
  (verify)

Nedaplatin (INN, marketed under the tradename Aqupla) is a platinum-based antineoplastic drug which is used for cancer chemotherapy.[1] The complex consists of two ammine ligands and the dianion derived from glycolic acid.

Platinum-based drugs are widely employed as antineoplastic agents, especially cisplatin and carboplatin. Due to issues of their toxicity and number of cisplatin-resistant cancer cells, other platinum derivatives have been developed. Nedaplatin is one example of such new drugs.[2]

References[edit]

  1. ^ Apps, M. G., Choi, E. H. Y., Wheate, N. J. (2015). "The state-of-play and future of platinum drugs". Endocrine-related Cancer. 22 (4): 219–233. doi:10.1530/ERC-15-0237. PMID 26113607. 
  2. ^ Johnstone, Timothy C.; Park, Ga Young; Lippard, Stephen J. (2014-01-01). "Understanding and Improving Platinum Anticancer Drugs – Phenanthriplatin". Anticancer research. 34 (1): 471–476. ISSN 0250-7005. PMC 3937549Freely accessible. PMID 24403503. 

External links[edit]