Neha began playing at age 5 and at age 9 moved with her sister, Shikha Uberoi to attend Saddlebrook Tennis Academy in Tampa, Florida. At 16 years old, Neha attended her freshman year at Princeton University, where she was All-Ivy League Rookie of the Year in 2003 and named an All-American in singles and doubles the same year. She took a 6 year leave of absence from Princeton University to play on the World Tennis Association tour.
Neha retired from professional tennis in 2008 and graduated from Princeton with a degree in Sociology in 2012. In 2016 she got married. She co-founded a non-profit organization South Asians in Sports.
Neha Uberoi is one of five sisters who all played tennis. Her father, Mahesh, is a serial entrepreneur and managed her tennis career; her mother, Madhu, is a homemaker; and she has two older sisters, Diya and Shikha Uberoi (plays on tour), and two younger sisters, Nikita and Nimita. She speaks Hindi, English and Spanish. Neha loves to visit relatives in Mumbai, India.