Neutrophil cytosolic factor 2

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NCF2
Protein NCF2 PDB 1e96.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases NCF2, NCF-2, NOXA2, P67-PHOX, P67PHOX, Neutrophil cytosolic factor 2
External IDs MGI: 97284 HomoloGene: 374 GeneCards: 4688
RNA expression pattern
PBB GE NCF2 209949 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000433
NM_001127651
NM_001190789
NM_001190794

NM_010877

RefSeq (protein)

NP_000424.2
NP_001121123.1
NP_001177718.1
NP_001177723.1

NP_035007.1

Location (UCSC) Chr 1: 183.56 – 183.59 Mb Chr 1: 152.8 – 152.84 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Neutrophil cytosol factor 2 is a protein that in humans is encoded by the NCF2 gene.

This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein complex known as NADPH oxidase found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease.[1]

References[edit]

Further reading[edit]