New York Genome Center

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New York Genome Center
Nygenomelogo-color300px.png
Established2011 (2011)
Research typeBasic (non-clinical), Clinical research and translational research
Field of research
Genomics, Bioinformatics, DNA sequencing, Whole genome sequencing
PresidentCheryl A. Moore, President & COO[1]
DirectorTom Maniatis, PhD,[2] Scientific Director & CEO
LocationNew York City, New York, United States
Affiliations
Harold E. Varmus, MD
WebsiteNew York Genome Center

The New York Genome Center (NYGC) is a 501(c)(3) nonprofit biomedical research organization in New York, New York.[4] A collaboration of academic, medical and industry leaders in New York and other partners throughout the country, the New York Genome Center focuses on translating genomic research into clinical solutions for serious diseases. NYGC faculty hold joint academic appointments at its member institutions and lead clinically focused genomic studies in a number of disease areas, including pediatric and adult cancer, asthma, autism, Alzheimer’s disease, ALS and other serious neurodegenerative diseases. NYGC scientists bring a multidisciplinary and in-depth approach to the field of genomics, conducting research in a wide range of areas, including single cell genomics, gene engineering, population and evolutionary genomics, technology and methods development, statistics, computational biology and bioengineering.[5] In 2017, co-founder Tom Maniatis was appointed Scientific Director and Chief Executive Officer of the New York Genome Center.[6]

Founding[edit]

The Center was legally founded in November 2011 as a collaboration among eleven academic institutions to advance genome research,[7] based on leadership from Tom Maniatis[8] and financial support of $2.5 million from each institution as well as a number of private philanthropists, including then Mayor Michael Bloomberg, James Simons and Russell Carson.[7] One year after its founding, NYGC recruited Robert B. Darnell as President and Scientific Director,[9] and formally opened in a multi-story building at 101 Avenue of the Americas.[10][11] on September 19–20, 2013.[12][13]

The 12 founding institutions (Albert Einstein College of Medicine joined the original 11 institutions on April 2013)[14] were:

Funding[edit]

The Center's funding sources include US and New York state governments, a contract with 10 medical institutes for central management of clinical data, and charitable foundations.[10] This includes funds pledged by the Simons Foundation and the Carson Family Charitable Trust of up to $100 million from 2016 to 2019.[15][16]

Government funding has included a $55 million grant from New York State to support genomic medicine [17] and a $40 million grant for establishing a Center for Common Disease Genomics from the National Human Genome Research Institute, the aim of which is to describe a comprehensive list of genes underlying common diseases.[16] Additionally, the Center and Weill Cornell Medicine received a National Cancer Institute grant to support a joint cancer genomics data center for the research and clinical interpretation of tumors, a part of the ongoing development of The Cancer Genome Atlas; the grant provides $490,000 per year for five years.[18] The Center was also awarded a $13.5 million contract to conduct whole genome sequencing and analysis for the National Heart, Lung, and Blood Institute's TOPMed program.[19][a]

In 2017, New York State committed $17 million in capital improvements for the New York Genome Center to house JLABS@NYC, a life sciences incubator set to open in summer 2018.[20]

Faculty[edit]

  • Hemali Phatnani, PhD | Director of the Center for Genomics of Neurodegenerative Disease[21]
  • Greg Hannon, PhD | Senior Associate Core Member & Director of Cancer Genomics[22]
  • Marcin Imielinski, MD, PhD | Core Faculty Member, Assistant Investigator[23]
  • Ivan Iossifov, PhD | Core Faculty Member, Assistant Investigator[22]
  • Dan A. Landau, MD, PhD | Core Faculty Member, Assistant Investigator[24]
  • Tuuli Lappalainen, PhD | Core Faculty Member, Assistant Investigator[25]
  • Joe Pickrell, PhD | Core Faculty Member, Assistant Investigator[26]
  • Neville Sanjana, PhD | Core Faculty Member, Assistant Investigator[27]
  • Rahul Satija, PhD | Core Faculty Member, Assistant Investigator[28]
  • Harold E. Varmus, MD | Senior Associate Core Member[29][30]
  • Michael Wigler, PhD | Senior Associate Core Member[31]
  • David Goldstein, PhD | Associate Member[32]
  • Jerome B. Posner, MD | Clinical Associate Member[33]
  • Simon Tavaré, PhD | Senior Researcher[34]
  • Yaniv Erlich, PhD | Adjunct Core Member[35]

Notes[edit]

  1. ^ NYGC is among several recipients, another being the Broad Institute.

Recent Publications[edit]

References[edit]

  1. ^ "Cheryl Moore, Hilde Windels, and more". People in the News. genomeweb. 11 September 2015. Retrieved 20 October 2017. (Registration required (help)).
  2. ^ "Tom Maniatis". People in the News. genomeweb. 18 August 2017. Retrieved 20 October 2017. (Registration required (help)).
  3. ^ "About Us". New York Genome Center. Our Members.[self-published source]
  4. ^ Duignan, Christopher (13 August 2015). "Form 990: Return of Organization Exempt From Income Tax" (PDF). GuideStar. p. 1. Retrieved 22 November 2016. (Registration required (help)).
  5. ^ http://www.nygenome.org/wp-content/uploads/2017/04/AAG_Formatted.pdf[full citation needed]
  6. ^ "Tom Maniatis Andy Page, Brian Caveney, More". People in the News. genomeweb. 25 August 2017. Retrieved 20 October 2017.
  7. ^ a b "New York Genome Center Launches Unprecedented Collaboration of 11 Leading Medical/Research Institutions". newsroom.cumc.columbia.edu. November 3, 2011. Retrieved 26 March 2017.
  8. ^ "Tom Maniatis' Dream of a NY Genome Center Becomes a Big Apple Reality". www.xconomy.com. Retrieved 26 March 2017.
  9. ^ "Robert Darnell named President of New York Genome Center". Rockefeller University Newswire. November 28, 2012. Retrieved 26 March 2017.
  10. ^ a b Rosenthal, Eric T. (9 March 2016). "A New 'Manhattan Project': New York Genome Center". MedPage Today. Retrieved 21 November 2016.
  11. ^ Hargittai, István; Hargittai, Magdolna (2016). New York Scientific: A Culture of Inquiry, Knowledge, and Learning. Oxford, United Kingdom: Oxford University Press. p. 167. ISBN 9780191084683.
  12. ^ Maher, Brendan (2013). "Biomedical-research hub opens in Manhattan". Nature. doi:10.1038/nature.2013.13740.
  13. ^ Matheson, Sarah. "Genome Center Opens in New York". Epoch Times. Retrieved 26 March 2017.
  14. ^ "Einstein joins NYGC as 12th Founding Member". Retrieved 26 March 2017.
  15. ^ Di Mento, Maria (25 January 2016). "$100 Million for Genome Center and $75 Million for Hospital". Gifts Roundup. The Chronicle of Philanthropy. New York Genome Center. Retrieved 22 November 2016.
  16. ^ a b Lagasse, Jeff (21 January 2016). "New York Genome Center scores $100 million from James Simons, Russell Carson". Healthcare Finance. Retrieved 22 November 2016.
  17. ^ "Governor Cuomo Announces Partnership between New York Genome Center and IBM Watson Group". Retrieved 27 March 2017.
  18. ^ "Weill Cornell Medicine and the New York Genome Center Awarded NCI Grant to Create Genomic Data Center". Bio-IT World. 3 November 2016. Retrieved 22 November 2016.
  19. ^ "NY Genome Center Wins $13.5M from NHLBI Precision Medicine Program". GenomeWeb. 29 October 2015. Retrieved 22 November 2016. (Registration required (help)).
  20. ^ "J&J, fueled by $17M in state cash, starts work on 30-startup JLABS incubator to address NYC lab shortage | FierceBiotech". www.fiercebiotech.com. Retrieved 2018-03-06.
  21. ^ http://www.alsa.org/research/our-approach/inspiring-partnerships/strategic-initiatives/new-york-genome-center.html?referrer=https://www.google.com/?referrer=https://en.wikipedia.org/
  22. ^ a b https://www.genomeweb.com/resources/people-news/greg-hannon-ivan-iossifov
  23. ^ https://news.weill.cornell.edu/news/2016/11/weill-cornell-medicine-and-the-new-york-genome-center-awarded-nci-grant-to-create
  24. ^ http://vivo.med.cornell.edu/display/cwid-dal3005
  25. ^ https://systemsbiology.columbia.edu/faculty/tuuli-lappalainen
  26. ^ https://www.genomeweb.com/business-news/columbia-nygc-researchers-spin-out-new-company-1m-funding
  27. ^ https://www.crunchbase.com/person/neville-sanjana
  28. ^ http://engineering.nyu.edu/people/rahul-satija
  29. ^ https://www.genomeweb.com/cancer/varmus-resigns-nci-director-plans-open-research-lab-weill-cornell-assist-ny-genome-center
  30. ^ https://www.nature.com/news/harold-varmus-to-resign-as-head-of-us-cancer-institute-1.17063
  31. ^ http://www.nygenome.org/lab-groups-overview/wigler-lab/
  32. ^ http://www.columbiamedicinemagazine.org/ps-news/fall-2014/david-goldstein-direct-columbia%E2%80%99s-institute-genomic-medicine
  33. ^ "Jerome B. Posner, MD, Joins The New York Genome Center as Clinical Member - New York Genome". New York Genome. Retrieved 2017-11-02.
  34. ^ http://www.nygenome.org/news/simon-tavare-phd-joins-new-york-genome-center-senior-researcher/
  35. ^ http://www.cs.columbia.edu/2015/erlich-new-prof/