Niceritrol

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Niceritrol
Niceritrol.png
Systematic (IUPAC) name
3-[(pyridin-3-yl)carbonyloxy]-2,2-bis({[(pyridin-3-yl)carbonyloxy]methyl})propyl pyridine-3-carboxylate
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
ATC code C10AD01 (WHO)
PubChem CID 4476
ChemSpider 4321 N
UNII F54EHJ34MV YesY
KEGG D01754 YesY
Chemical data
Formula C29H24N4O8
Molar mass 556.523 g/mol
 NYesY (what is this?)  (verify)

Niceritrol is a niacin derivative used as a hypolipidemic agent. It is an ester of pentaerythritol and nicotinic acid, has general properties similar to those of nicotinic acid (Nicotinamide), to which it is slowly hydrolysed. Niceritrol has been used as a lipid regulating drug in hyperlipidaemias and as a vasodilator in the treatment of peripheral vascular disease.[1][2]

References[edit]

  1. ^ Owada A.; Suda S; Hata T. (2003). "Antiproteinuric effect of niceritrol, a nicotinic acid derivative, in chronic renal disease with hyperlipidemia: a randomized trial.". Am J Med 114 (5): 347–53. PMID 12714122. 
  2. ^ Truven Health Analytics Inc. (May 8, 2008). "Niceritrol". Micromedexsolutions.com. Retrieved December 14, 2014.