On the 2010 England tour to Australia he was named man of the match in the second test victory 21–20, helping secure England's first win down under for seven years. Later that year he captained his country during the autumn internationals against Samoa which England won 26-13.
He was involved in the 2011 Rugby Union World Cup and was reported to be the player to have reacted to England's quarter-final defeat by France in Auckland by joking: "There's £35k just gone down the toilet."
During 2012, despite being regarded as the 'best No. 8 in England', he found his road into the England squad blocked, but he has since enjoyed success with Harlequins helping them to win the Amlin Cup in 2011 and the club's first-ever English Premiership title in 2012.
In the penultimate game of the 2013/14 season, against Bath, Nick became the most capped Harlequin in the professional era, with 233 appearances.
After being in the international wilderness for just over 3 years Nick was recalled to the England squad for the 2015 Six Nations. In the opening game he came on as a substitute for England in their 21-16 win over Wales at the Millenium Stadium in Cardiff. In the second game, he scored a try against Italy and thus became the oldest player ever to score for England. He won his 50th cap away to Ireland.