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Nicolae Haralambie (August 27, 1835 in Chișinău – April 3, 1908 in Bucharest) was a Romanian soldier and politician.
In 1861, he headed the Bucharest police. As a colonel, he took part in the dethronement of Prince Alexandru Ioan Cuza in 1866, subsequently serving in a regency alongside Lascăr Catargiu and Nicolae Golescu.
He served as War Minister from August 6, 1866 to February 7, 1867.