Nicotiana benthamiana

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Nicotiana benthamiana
Nicoatiana benthamiana plant.jpg
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Solanales
Family: Solanaceae
Genus: Nicotiana
Species: N. benthamiana
Binomial name
Nicotiana benthamiana

Nicotiana benthamiana is a close relative of tobacco and species of Nicotiana indigenous to Australia.

The herbaceous plant is found amongst rocks on hills and cliffs throughout the northern regions of Australia. Variable in height and habit, the species may be erect and up to 1.5 metres or sprawling out no taller than 200 millimetres. The flowers are white.[1]

The plant was used by peoples of Australia as a stimulant - it contains nicotine and other alkaloids - before the introduction of commercial tobacco (N.tabacum and N.rustica). The indigenous names for it include tjuntiwari and muntju. It was first collected on the north coast of Australia by Benjamin Bynoe on a voyage of the HMS Beagle in 1837.[2]

A synonym for this species is Nicotiana suaveolens var. cordifolia, a description given by George Bentham in Flora Australiensis in 1868. This was transferred to Nicotiana benthamiana by Karel Domin in Bibliotheca Botanica (1929), retaining the author's name in the specific epithet.[3]

N. benthamiana is considered by a growing scientific community as a model organism for performing plant research. For example, the leaves are rather frail and can be injured in experiments to study ethylene synthesis. Ethylene is a plant hormone which is secreted, among other situations, after injuries. Using gas chromatography, the quantity of ethylene they emitted can also easily be measured. Due to the large number of plant pathogens able to infect it, N. benthamiana is widely used in the field of plant virology. It is also an excellent target plant for agroinfiltration[4] and a platform for industrial production of recombinant pharmaceutical proteins, including monoclonal antibodies.[2]

N. benthamiana is also a common plant used for pharming; for example, the drug ZMapp was produced in one of these plants.


Nicotiana benthamiana, leaf
  1. ^ Spooner. FloraBase
  2. ^ a b Patton, J. How Owensboro tobacco grew a possible miracle drug to treat Ebola August 9, 2014.
  3. ^ APNI id: 22952, 39749
  4. ^ "Agroinfiltration is a versatile tool that facilitates comparative analyses of Avr9/Cf-9-induced and Avr4/Cf-4-induced necrosis". Mol. Plant Microbe Interact. 13 (4): 439–46. April 2000. doi:10.1094/MPMI.2000.13.4.439. PMID 10755307.