Nijō Akizane (二条 昭実, December 2, 1556 – August 23, 1619), son of regent Nijō Haruyoshi, was a Japanese kugyō (court noble) of the Azuchi-Momoyama period and the early Edo period. He held a regent position kampaku two times: once in 1585, and again from 1615 to 1619. He married a daughter of daimyo Oda Nobunaga and the couple adopted Kujō Yukiie's son, who became known as Nijō Yasumichi.
- ネケト. 二条家（摂家） (in Japanese). Retrieved 2007-09-14.
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