Nodal marginal zone B cell lymphoma

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Nodal marginal zone B cell lymphoma
SpecialtyHematology, oncology

Nodal marginal zone B cell lymphoma (NMZL) is an uncommon form of marginal-zone lymphoma[1] that can produce colonization of the follicles in the lymph node.[2][3] It is a form of low grade lymphoma with similar incidence in men and women and a mean age of 61 years (range 26–92 years). It is often associated with Sjogren syndrome. It shows interfollicular infiltrate of monocytoid, centrocyte-like B cells that are 2–3× larger than small lymphocytes with partial/total effacement of lymph node architecture.


  1. ^ Ferreri AJ, Zucca E (September 2007). "Marginal-zone lymphoma". Crit. Rev. Oncol. Hematol. 63 (3): 245–56. doi:10.1016/j.critrevonc.2007.04.009. PMID 17583528.
  2. ^ Naresh KN (February 2008). "Nodal marginal zone B-cell lymphoma with prominent follicular colonization - difficulties in diagnosis: a study of 15 cases". Histopathology. 52 (3): 331–9. doi:10.1111/j.1365-2559.2007.02951.x. PMID 18269584. S2CID 205299373.
  3. ^ Kojima M, Nakamura S, Murase T, et al. (January 2005). "Follicular colonization of nodal marginal-zone B-cell lymphoma resembling follicular lymphoma: report of 6 cases". Int. J. Surg. Pathol. 13 (1): 73–8. doi:10.1177/106689690501300110. PMID 15735858. S2CID 23552907.[permanent dead link]

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