From Wikipedia, the free encyclopedia
Jump to: navigation, search
Systematic (IUPAC) name
Legal status
Legal status
CAS Number 467-15-2 YesY
ATC code none
PubChem CID 9925873
ChemSpider 8101508 N
Chemical data
Formula C17H19NO3
Molar mass 285.337 g/mol
 NYesY (what is this?)  (verify)
Not to be confused with Norco (medication).

Norcodeine is an opiate analogue that is the N-demethylated derivative of codeine. It has relatively little opioid activity in its own right,[1] but is formed as a metabolite of codeine following ingestion.[2]

Norcodeine is a Schedule I Narcotic controlled substance in the USA with the ACSCN of 9309 and zero annual manufacturing quota. The salts in use are the acetate (free base conversion ratio 0.826), hydroiodide (0.662), hydrochloride (0.759), nitrate (0.819), platinichloride (0.582), and sulphate (0.744).[3]

See also[edit]


  1. ^ Fraser HF, Isbell H, Van Horn GD. Human pharmacology and addiction liability of norcodeine. Journal of Pharmacology and Experimental Therapeutics. 1960 Jun;129:172-7. PMID 13824628
  2. ^ Posey BL, Kimble SN. High-performance liquid chromatographic study of codeine, norcodeine, and morphine as indicators of codeine ingestion. Journal of Analytical Toxicology. 1984 Mar-Apr;8(2):68-74. PMID 6716978.
  3. ^