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Levonorgestrel.svg Dextronorgestrel.svg
Systematic (IUPAC) name
Clinical data
AHFS/ Micromedex Detailed Consumer Information
MedlinePlus a602008
Legal status
Pharmacokinetic data
Biological half-life 5–14 hours
CAS Registry Number 6533-00-2 YesY
ATC code G03AA06 G03FA10 G03FB01 (only combinations with estrogens)
PubChem CID: 16051930
ChemSpider 10481953 YesY
UNII 3J8Q1747Z2 YesY
KEGG D00954 YesY
Chemical data
Formula C21H28O2
Molecular mass 312.446 g/mol
 N (what is this?)  (verify)

Norgestrel is an old progestin that has been used in hormonal contraceptives. Norgestrel is a mixture of two stereoisomers, dextro-norgestrel (CAS# 797-64-8 ) and levo-norgestrel (CAS# 797-63-7 ).[1] Only levonorgestrel is biologically active.[2] Therefore, while some medications may contain dextronorgestrel, they are often labeled in terms of their levonorgestrel content only, ignoring the inert isomer.[citation needed]

Norgestrel has also been used as an emergency contraceptive in the Yuzpe regimen.[3]

See also[edit]


  1. ^ Mutschler, Ernst; Schäfer-Korting, Monika (2001). Arzneimittelwirkungen (in German) (8 ed.). Stuttgart: Wissenschaftliche Verlagsgesellschaft. pp. 442f. ISBN 3-8047-1763-2. 
  2. ^ Benagiano, G; Carrara, S; Filippi, V (2009). "Safety, efficacy and patient satisfaction with continuous daily administration of levonorgestrel/ethinylestradiol oral contraceptives". Patient preference and adherence 3: 131–43. PMC 2778424. PMID 19936155. 
  3. ^ Yuzpe, A. A.; Smith, R. P.; Rademaker, A. W. (1982). "A multicenter clinical investigation employing ethinyl estradiol combined with dl-norgestrel as postcoital contraceptive agent". Fertility and sterility 37 (4): 508–13. PMID 7040117.