Norgestrel
From Wikipedia, the free encyclopedia
 |
|
|
|
| Clinical data | |
|---|---|
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| MedlinePlus | a602008 |
| ATC code | |
| Legal status | |
| Legal status |
|
| Pharmacokinetic data | |
| Biological half-life | 5–14 hours |
| Identifiers | |
|
|
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ECHA InfoCard | 100.026.758 |
| Chemical and physical data | |
| Formula | C21H28O2 |
| Molar mass | 312.45 g·mol−1 |
| 3D model (JSmol) | |
|
|
|
|
  (what is this?) (verify) |
|
Norgestrel (INN, USAN, BAN, JAN; brand names Logynon, Nordette, Eugynon, Microgynon, Ovran, Ovranette, Trinordiol, and numerous others) is a steroidal progestin that has been used in hormonal contraceptives. It is a mixture of two stereoisomers, dextronorgestrel and levonorgestrel.[1][2] Only levonorgestrel is biologically active.[2][3] Therefore, while some medications may contain dextronorgestrel, they are often labeled in terms of their levonorgestrel content only, ignoring the inert isomer.[citation needed]
Norgestrel has also been used as an emergency contraceptive in the Yuzpe regimen.[4]
See also[edit]
References[edit]
- ^ a b Mutschler, Ernst; Geisslinger, Gerd; Kroemer, Heyo K. & Schäfer-Korting, Monika (2001). Mutschler Arzneimittelwirkungen: Lehrbuch der Pharmakologie und Toxikologie [Mutschler's Drug interactions: Textbook of Pharmacology and Toxicology] (in German) (8th ed.). Stuttgart, DEU: Wissenschaftliche Verlagsgesellschaft. pp. 442f. ISBN 3804717632.
- ^ a b "Levonorgestrel". DrugBank. Canadian Institutes of Health Research.
- ^ Benagiano G; Carrara S & Filippi V (2009). "Safety, Efficacy and Patient Satisfaction with Continuous Daily Administration of Levonorgestrel / Ethinylestradiol Oral Contraceptives". Patient Preference and Adherence. 3: 131–143. PMC 2778424
. PMID 19936155. - ^ Yuzpe AA, Smith RP & Rademaker AW (1982). "A Multicenter Clinical Investigation Employing Ethinyl Estradiol Combined with dl-Norgestrel as Postcoital Contraceptive Agent". Fertility and Sterility. 37 (4): 508–513. PMID 7040117.
 |
This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it. |
 |
This article about a steroid is a stub. You can help Wikipedia by expanding it. |
